Opening Remark

Synaptic Highs: Unraveling Dopamine’s Grip on Addiction

Seeing in the cold - hibernation biology and its potential applications

Cellular senescence and rejuvenation

Chromatin remodeling checkpoints of islet homeostasis and function

Stem cell and vascular organoids

Encoding mechanisms of behavioral decisions

Chromatin remodeling regulates vascular smooth muscle cell identity

The role and mechanism of BRCA1 in placental trophoblast differentiation

GPCR Signal Transduction and Glucose Metabolism

Targeting molecular and network connectivity to modulate neuropsychiatric dysfunction

Locus coeruleus norepinephrine neurons in high-fat diet regulation of anorexia nervosa

The impact of estrogen on PRDX expression and ferroptosis in hepatocellular carcinoma

DreAM-Plus, an integrative inducible RNA switch for controlled genome editing in vivo

Inhibition of KLK8-PARP1 signal ameliorates pulmonary endothelial senescence and susceptibility to VILI in the elderly

AAV-HDR system rescues LMNA-related cardiomyopathy by EPHX2 nucleus localization

Structural and functional remodeling of anion exchanger SLC26A6 in cardiomyocytes after myocardial infarction

Translocation of GSDMD and RIPK3 to mitochondria synergistically exacerbates endothelial injury in Shiga toxin-induced HUS

Mechanism of PI4KA/PI4P axis regulation of lysosome-dependent cell death in the progression of oxalate nephropathy and the therapeutic potential of hydroxychloroquine

Insufficient S-sulfhydration of cAMP-response element binding protein 1 participates in kidney fibrosis via promoting epithelial-mesenchymal transition

A deterministic framework for dimensionality reduction reveals temporal gene regulatory dynamics

Multifunctionality of Tight Junction Transmembrane Proteins

Circadian Clock and Liver Injury

Decidual Macrophage Metabolism: A Missing Link in the Pathogenesis of Recurrent Spontaneous Abortion?

Amino Acid Transport and Regulation of Water Homeostasis

Discussion

The atlas and function of hypothalamus

Glial control of compulsive food seeking

Neuroimmune in the regulation of sympathetic tonicity and cardiovascular function

Brainstem NPY Neurons: Pivotal Players in Orchestrating Energy Intake and Expenditure

Zona Incerta neurons control binge eating

Discussion

Mechanisms of Myeloid-Biased Differentiation in Hematopoietic Stem Cells Under High-Altitude Hypoxia

Effects of Hypoxia at High Altitudes on Cognitive Function via the Regulation of Granule Cells in the Dentate Gyrus

Research Progress and Prospects of High Altitude Brain Science

Assessment of cerebral blood flow and glymphatic function in Acute mountain sickness: based on MRI ASL and DTI-ALPS

A Serum Proteomic Study of Patients with Cognitive Impairments in High Altitude

Discussion

The first principle of lifestyle physiology

Focusing on O₂ to CO₂ to understand the theory of Holistic Integrative Physiology (HIP)

Exploring the functional effects of cellular nutrition on epithelial cells and their relevance to lifestyle physiology in reproductive health

Health behaviors and emotional well-being among Chinese college students

Eexercise and glycine drives Ferroptosis Resistance Counteract Aging

Discussion

Central Dogma of Aging

Molecular Underpinnings of Exercise's Health-Promoting and Geroprotective Effects

Mechanistic Insights into Aging: From Cellular Senescence to Organ-Level Decline

Non-coding Regulation of Cellular Senescence and Related Diseases

Physiological Clocks of Aging and Their Interventions

Discussion

Basic and Clinical Research Progress on Vascular Aging

Identification of Endogenous Anti-Aging Factors in Longevity Populations

Endothelial Cell Senescence and HFpEF

The Role of Cellular Senescence in Breast Cancer Progression and Its Underlying Mechanisms

Inter-Organ and Tissue Regulation of Sarcopenia

Discussion

Inflammation-Driven Depression: Mechanisms and Biomarkers

Adolescent Depressive Disorder Management Practice

Acupoint stimulation therapy for domestic violence-associated depression and Alzheimer's disease: clinical efficacy and mechanistic study

The advantageous feature of Yueju Pill in rapid antidepressant effects：the findings of novel mechanism, compound synergism and clinic outcomes

Guidelines for the diagnosis and treatment of depressive disorders by integrating Chinese and Western medicine (English edition)

Discussion

TNIK as a Molecular Switch Regulating Platelet Function in Hemostasis and Hyperlipidemia-Associated Thrombosis

New Risk Factor for Macrothrombocytopenia and Novel Therapeutic Target for Thrombo-Inflammatory Diseases

Platelet NLRP6 regulates thromboinflammation in sepsis

BAD-glucokinase axis regulates platelet activation and thrombosis

Discussion

Intelligent Medicine: Ethical Risks and Boundary Exploration of Medical Artificial Intelligence

AI Dual-Driven "Atlas + Experiment": Competency-Oriented Practice to Empower the Cultivation of Innovative Medical Talents

Digital and intelligent empowerment of drug safety monitoring

Digital Twin of Healthcare based on Big Medical Data

Intelligent medical imaging and processing

Discussion

Emerging Roles of Mitochondrial Calcium in Cardiac Pathophysiology

Multifaceted functions of Junctophilin-2 in the heart

Development of CMYA5-based gene therapy to regulate RYR2 activity

Transcriptional regulation of calcium signaling in cardiomyocytes

Discussion

Aerobic exercise attenuates nicotine addiction by regulating the ventral hippocampus-nucleus accumbens circuit

A Comparative Analysis of Methodologies for Assessing Metabolic Flexibility in Different Physiological States: Energy intake Versus Exercise-induced Energy

A Cellular Mechanism of Skeletal Muscle Fiber Type Conversion

Exercise-Mediated Brain-Heart Interorgan Signaling Modulates Aging Heart Function

Mechanistic Study of Exercise Ameliorating Skeletal Muscle Atrophy

Discussion

Mechanomolecular signaling of GPIb-IX in platelet clearance

Erythroid development and diseases

From multidimensional chromatin reorganization to immunomodulatory function of erythroid cells

Cellular barcoding reveals native and stress hematopoiesis

Circadian immune system

Immunotherapy of hematologic malignancies by targeting myeloid cells

Discussion

Clinical research and trial of single-cell measurements

Early pathogenesis and novel research tool of pulmonary fibrosis

Airway remodeling in asthma: from clinical problems to basic research

Super-enhancer-driven HCG20 regulates pulmonary endothelial cell dysfunction through U2AF2-mediated pre-mRNA alternative splicing

EphB4 Phase Separation: A New Target for Pulmonary Hypertension

Discussion

Modulation of inflammation and pain by electroacupuncture

Chronic pain-induced functional and structural alterations in the brain

Extracellular matrix remodeling in chronic pain and affective disorders

Neuron-satellite cell interaction regulates trigeminal neuropathic pain

Decoding the Pathophysiology of Pain and Its Implications for Emotional Regulation

Discussion

The Vagal NG Neuron-PNEC Axis Regulates Pulmonary Immunity

Medullary Circuits for Control of Respiratory Homeostasis

Exploring Heart-Brain-Respiration Coupling Characteristics

Clinical Advances in Obstructive Sleep Apnea Syndrome

Interaction Between Breathing and Behavior

Discussion

The Role of Dynamic Ca2+ Signals in Specifying Autophagosome Initiation

Unraveling the Enigma of Organ-Specific Vasculature in Health and Disease

Matrix-Vascular Crosstalk in Vascular Homeostasis

Modular Assembly of Arterial Organoids Promotes Blood Perfusion to Alleviate Ischemic Diseases

Multifaceted Mechanisms Governing Endothelial and Immune Cell Function in Vascular Homeostasis

Precision Cardiac Gene Therapy via improved AAV vectors

Adipocyte GIPR Potentiates Leptin Signaling to Drive Superior Metabolic Efficacy of GLP-1R/GIPR Co-agonism

Pathology-Specific Role of 5-HT2B Receptor in Vascular Remodeling and Its Potential as a Therapeutic Target

DDR1 is a Novel Mechanosensor in Vascular Smooth Muscle and Endothelial Cells

Endothelial serotonin receptor 1B acts as a mechanosensor to drive atherosclerosis

Microglia-Neuron Interactions in Regulating Emotion and Pain

Brain regulation of gastric dysfunction induced by stress

Chronic pain and dementia: a brain aging framework

A sensory-motor-sensory circuit underlies antinociception ignited by primary motor cortex

The neural mechanisms of stress and related psychiatric disorders

Decoding the Neural Mechanisms of Anxiety: From Sexual Dimorphic Pathogenesis to Therapeutic Targets

NPTX-dependent engram network recruitment and stabilization facilitate memory formation, consolidation and extinction

Neural Mechanisms Underlying Motor-Emotion Integration

Pathogenic Mechanisms of the High-Risk Autism Gene Scn2a

Physical exercise alleviates anxiety disorders via modulating synaptic protein lactylation

 Cryo-EM Reveals Dynamic Protein Conformations Under Physiological Conditions

Regulatory mechanisms of proliferation and differentiation of skeletal stem cell lineages in relation to skeletal diseases

Uremic toxins promote renal fatty acid synthesis and fibrosis via activating aryl ydrocarbon receptor

The multidimensional roles of monosaccharides drive chronic inflammation and metabolic dysregulation in PCOS pathogenesis

Neuroimmune interactions in the intestine

Pausing and restarting life from reversible suspended animation

Evidence for an immunomodulatory function of fumarate

Exploring new compounds and new targets to delay brain aging

From physiology to pathology: novel paradigms in the brain-muscle communication network

Neural Vesicle GABA Suppresses Lysosomal acid Lipase LIPL-1/LIPA-Mediated Intestinal Innate Immunity to Promote Anoxic Tolerance

Discussion

TIGER portal: a tool for gene therapy of frameshift diseases

The regulation of gene expression in the cochlea and its applications in gene therapy for hearing loss

Structure-based Classification of Hearing Loss-Related Variants Driven by Artificial Intelligence

Hearing sound with TMC1/2 proteins

Molecular and genetic mechanisms underlying cochlear hair cell development and regeneration

Discussion

Neuroplasticity in experimental models of stress-related brain disorders

Cross-taxon modeling of stress: translational lessons from rodents and zebrafish

Neuroinflammation in depression and other stress-related conditions

Impact of the metabolic energy sources and stress on astroglia in health and disease

Dissecting the role of microglia and integrated stess response (ISR) in experimental models of chronic stress

Discussion

Cerebellar Regulation of Motor-Metabolic Homeostasis: Evolutionary and Functional Perspectives

Cholinergic signaling differentially regulates song premotor circuits to stabilize birdsong

Gut microbiota-bile acids crosstalk involved in the regulation of thermogenesis and energy metabolism in sleep deprived mice

Gut microbiota-bile acids crosstalk involved in the regulation of thermogenesis and energy metabolism in sleep deprived mice

Unique lipid accumulation mechanism in Daurian ground squirrel, a mammalian hibernator

Cell autonomous and non-autonomous mechanisms in cancer resistance of subterranean mammals

Cell autonomous and non-autonomous mechanisms in cancer resistance of subterranean mammals

Discussion

Anti-obesity drug mechanisms and drug discovery in human cellular models

Identification of a neural basis for energy expenditure in the arcuate hypothalamus

A brain-to-gut axis controls fat absorption

The mechanistic roles of endoplasmic reticulum stress in obesity associated ectopic lipid deposition

Acetate metabolism in vasculature

Discussion

The impact of high-intensity interval training, with or without hypoxia, on skeletal muscle glucose and lipid metabolism in young males and females

Mechanism of telomere-mitochondrial signaling axis in metabolic remodeling of heart failure

Loss of Ovarian Follicles in Adamts9 Knockout Zebrafish

G protein-coupled receptors in endocrine metabolism

White adipose tissue controls gut immunity and microbiota homeostasis via production of extracellular vesicles in ageing

Discussion

The Role of Sleep and Circadian Rhythms in the Precision Prevention of Alzheimer's Disease

Musculoskeletal Aging Risk Evaluation and Feature Analysis in Tai Chi Practitioners

Risk Assessment and Exercise Intervention for Musculoskeletal Disorders in Older Adults

Exploration and Validation of the Optimal Exercise to Improve Cognitive Abilities Among Community-Dwelling MCI Older Adult

Effects of Different Duration Endurance Exercise on the Expression of FOXO3α, MAFbx32 and MuRF1 of Skeletal Muscle in Olderly Mice

Discussion

Openning Remarks

Probiotics and Disorders of Gut-Brain interactions

Probiotics and Disorders of Gut-Brain interactions

Gut microbiome and metabolic health

Gut microbiome and metabolic health

Gender Difference in Microecology

Gender Difference in Microecology

Changes and significance of gut microbiota during the peri-operative period

Changes and significance of gut microbiota during the peri-operative period

Targeted Gut Microbiota Intervention Based on Novel Gut-Derived Functional Microbial

Targeted Gut Microbiota Intervention Based on Novel Gut-Derived Functional Microbial Strains

Free paper 1

Free paper 1

Free paper 2

Free paper 2

Free paper 3

Free paper 3

Summary

Study on the mechanism by which Astragaloside Ⅳ promotes post-ischemic neurogenesis through the PPARγ/miR-199a-5p/Cav-1 signaling pathway

The relationship between abnormal glucose and lipid metabolism and Alzheimer's disease and the mechanism of TCM treatment from liver and spleen

Development of Chinese and Western Medicines for Prevention and Treatment of Chemotherapy-Induced Peripheral Neuropathy

Osthole ameliorates chronic pruritus in 2,4-dichloronitrobenzene-induced atopic dermatitis by inhibiting Th2 cytokines production

Metabolomics analysis and target exploration of Pueraria lobata and its active component Puerarin in the treatment of pulmonary fibrosis

Hypothesis of the adominant receptors in acupuncture Deqi

Discussion

Mechanism of subthalamic deep brain stimulation

Brain Aging as a Critical Modulator of Amyloid-Induced Neurodegeneration: Evidence from Temporally Controlled APP Overexpression in Mice

Cortical-hypothalamic circuits in eating disorders and obesity

Targeting microbiota-derived galactosylceramide alleviates chronic pain-induced cognitive impairment

GHS-R1a: a new target for AD treatment

Discussion

Metabolic impact of the small intestine, kidney and the brain

TBD

Identification of bladder mucosa as the most dominant source for ROS production in the body – pathophysiological implications

Molecular mechanism underlying nutrient and stress sensing by intestinal stem cells

Mechanical Sensing in Enteroendocrine Cells and Metabolic Regulation

Discussion

Molecular physiology of the lysosome

Structural biology of ion channel complex in the sperm

Decoding sensory inputs by ion channels and receptors

Thermal activation of temperature sensing ion channels

Discussion

Structure-function and physiological roles of mechanically activated PIEZO channels

Cecal Resection Suppresses Ulcerative Colitis via an ILC2-Dependent

Spying on Neuromodulator Dynamics In Vivo by Constructing Multi-Color GRAB Sensors

Parallel Gut-to-Brain Pathways Orchestrate Feeding Behaviors

Microglia in the Periphery

Sympathetic functional units encoded by genetically defined postganglionic neurons

Discussion

Activated Protein C Signaling in the Age-related Cardiac Dysfunction and Alzheimer's Disease

Molecular Mechanism of Circular RNA in Regulating Myocardial Injury

Mitigation of Cardiac Hypertrophy and Fibrosis via a Circularized RNA Sponge Targeting miR-199a-5p and -3p

Remodeling of Phospholipid Metabolism and Aortic Dissection

Heterochromatin Safeguards Adult Cardiomyocyte Identity and Its Implications in Heart Failure

Discussion

Reprogramming the heart for repair and regeneration

The 18th Chang Hsi-Chun Forum on Physiological Sciences for Young Scholars Award

Excellent Poster Presenter Award

Concluding Remark

From wind-cold stress to TNFR2-targating immunotherapy

Brain and stress: from adaptation to disease

The immunological basis of intestinal spasm induced by stress

The modulation of synaptic protein lactylation by chronic stress and physical exercise

Ligand modulation mechanisms of KCNQ channels in human health and diseases

Discussion

Axon Regeneration and Functional Rewiring After Adult Central Nervous System Injury

Capturing totipotency in human cells by splicing repression

Neural stem cell mechanism study

Basic and Clinical Translation Research on Gene Therapy for Hereditary Deafness

Discussion

Exercise is Medicine and Beyond

New players in ASCVD with chronic renal failure

Uremic toxins in renal lipid dysregulation and fibrosis

Chromatin remodeling and metabolic regulation

Discussion

Fatty Acid Metabolism Disorders in Renal Tubules and Diabetic Kidney Disease

Construction of The Molecular Atlas of Kidney Diseases

MAD2B and Diabetic Kidney Disease

HNF4A Regulated APEH Deficiency Promotes UPR Activation in Diabetic Kidney Disease

Discussion

Opening Remarks

Introduction of the Committee

Present appointment letters

Group Photo

Remarks

Self-introductions and suggestions for committee development by members